Indirect immunofluorescence to demonstrate lichen planus specific antigen (LPSA) in lichen planus
نویسندگان
چکیده
منابع مشابه
Lichen planus specific antigen and antibodies--in a patient with generalized lichen planus.
A 43-year-old man with generalized lichen planus demonstrated serum antibodies against autologous lesional skin. Indirect immunofluorescence using serum and papular lesional skin revealed a lichen planus specific antigen found only in the granular layer. The specific tissue antigen was not detected in normal skin from this patient, in normal skin from patients with skin disorders other than lic...
متن کاملWhen is lichen planus lichen planus.
T ERMATOSES of diverse etiology have been -I-~ reported to give rise to skin and mucous membrane lesions whose morphology, symptomatology, course, and microscopic picture cannot be distinguished from lichen planus. Drugs,1-6 vaccines,7 contact with chemicals,8-'3 and exposure to ultraviolet light and Grenz rays14 are prominent among the causative agents which have been observed to produce liche...
متن کاملLichen planus
Lichen planus is a rare inflammatory disease that affects the skin, mucous membranes, nails, and hair. It is characterized by shiny, polygonal, itching papules which vary in size and location. In the Anglo-American literature, the clinical characteristics of lichen planus are known by the four p's – purple, polygonal, pruritic, papules.The etiology and pathogenesis of disease are not well under...
متن کاملLichen Planus
Copyright © 2012 Massachusetts Medical Society. A 53-year-old woman presents with intensely itchy skin lesions and burning in her mouth, which makes eating difficult. These signs and symptoms have become progressively evident during the past several weeks. Examination of her skin and oral cavity reveals violaceous, polygonal papules, mainly on the flexural aspect of the wrists and ankles and in...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology
سال: 2006
ISSN: 0378-6323
DOI: 10.4103/0378-6323.27750